Fenbendazole is an anthelmintic that destroys microtubules, which cancer cells depend on to survive and multiply. It also interferes with cancer cell ability to metabolize sugar, which they require for energy. It also stimulates production of p53, a gene cancer patients may lack that can keep cells from proliferating and spreading. Berberine is another natural substance that works in combination with fenbendazole to limit cancer cell multiplication and stop cancer cells from taking up glucose.
During facility treatment with a sterilizable diet containing the rodent pinworm medication sanare lab fenbendazole, an established human lymphoma xenograft model in C.B-17/Icr-prkdcscid/Crl (SCID) mice failed to grow. Since the fenbendazole-treated diet was also supplemented with additional vitamins to compensate for vitamin losses during sterilization, this study was designed to determine whether the fenbendazole and/or supplemental vitamins caused the observed inhibition of tumor growth.
Complete blood counts were performed on each mouse before and at the end of the study. Initial counts did not differ between test and control groups, but at study termination the fenbendazole plus vitamin group had significantly lower total white cell and neutrophil values than did the control group, suggesting that fenbendazole or the added vitamins suppressed the xenograft growth by limiting leukocyte responses. sanare lab fenbendazole